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12. Ibid.

13. Cai et al., “Molecular Signatures of Major Depression.” (See #3 above.)

14. Eisendrath, S. J., et al., “A Preliminary Study: Efficacy of Mindfulness-Based Cognitive Therapy Versus Sertraline as First-Line Treatments for Major Depressive Disorder,” Mindfulness 6, no. 3 (June 1, 2015): 475–482, doi:10.1007/s12671–014–0280–8; and Kuyken, W., et al., “The Effectiveness and Cost-Effectiveness of Mindfulness-Based Cognitive Therapy Compared with Maintenance Antidepressant Treatment in the Prevention of Depressive Relapse/Recurrence: Results of a Randomised Controlled Trial (the PREVENT Study),” Health Technology Assessment 19, no. 73 (September 2015): 1–124, doi:10.3310/hta19730.

15. Teasdale, J. D., et al., “Prevention of Relapse/Recurrence in Major Depression by Mindfulness-Based Cognitive Therapy,” Journal of Consulting and Clinical Psychology 68, no. 4 (August 2000): 615–623.

16. Teasdale, J., M. Williams, and Z. Segal, The Mindful Way Workbook: An 8-Week Program to Free Yourself from Depression and Emotional Distress (New York: Guilford Press, 2014).

17. Wolfson, W. & Epel, E. (2006). “Stress, post-traumatic growth, and leukocyte aging.” Poster presentation at the American Psychosomatic Society 64th Annual Meeting, Denver, Colorado, Abstract 1476.

18. Segal, Z., J. M. G. Williams, and J. Teasdale, Mindfulness-Based Cognitive Therapy for Depression, 2nd ed. (New York: Guilford Press, 2013): 74–75. (The Three minute breathing space is part of the MBCT program. Our breathing break is a modified version).

19. Bai, Z., et al., “Investigating the Effect of Transcendental Meditation on Blood Pressure: A Systematic Review and Meta-analysis,” Journal of Human Hypertension 29, no. 11 (November 2015): 653–662. doi:10.1038/ jhh.2015.6; and Cernes, R., and R. Zimlichman, “RESPeRATE: The Role of Paced Breathing in Hypertension Treatment.” Journal of the American Society of Hypertension 9, no. 1 (January 2015): 38–47, doi:10.1016/ j.jash.2014.10.002.

20. Morgan, N., M. R. Irwin, M. Chung, and C. Wang, “The Effects of Mind-Body Therapies on the Immune System: Meta-analysis,” PLOS ONE 9, no. 7 (2014): e100903, doi:10.1371/journal.pone.0100903.

21. Conklin, Q., et al., “Telomere Lengthening After Three Weeks of an Intensive Insight Meditation Retreat,” Psychoneuroendocrinology 61 (November 2015): 26–27, doi:10.1016/j.psyneuen.2015.07.462.

22. Epel, E., et al. “Meditation and Vacation Effects Impact Disease-Associated Molecular Phenotypes,” Translational Psychiatry (August 2016): 6, e880, doi: 10.1038/tp.2016.164.

23. Kabat-Zinn, J., Full Catastrophe Living: Using the Wisdom of Your Body and Mind to Face Stress, Pain, and Illness, rev. ed. (New York: Bantam Books, 2013).

24. Lengacher, C. A., et al., “Influence of Mindfulness-Based Stress Reduction (MBSR) on Telomerase Activity in Women with Breast Cancer (BC),” Biological Research for Nursing 16, no. 4 (October 2014): 438–447, doi:10.1177/1099800413519495.

25. Carlson, L. E., et al., “Mindfulness-Based Cancer Recovery and Supportive-Expressive Therapy Maintain Telomere Length Relative to Controls in Distressed Breast Cancer Survivors,” Cancer 121, no. 3 (February 1, 2015): 476–484, doi:10.1002/cncr.29063.

26. Black, D. S., et al., “Yogic Meditation Reverses NF– B and IRF-Related Transcriptome Dynamics in Leukocytes of Family Dementia Caregivers in a Randomized Controlled Trial,” Psychoneuroendocrinology 38, no. 3 (March 2013): 348–355, doi:10.1016/j.psyneuen.2012.06.011.

27. Lavretsky, H., et al.,”A Pilot Study of Yogic Meditation for Family Dementia Caregivers with Depressive Symptoms: Effects on Mental Health, Cognition, and Telomerase Activity,” International Journal of Geriatric Psychiatry 28, no. 1 (January 2013): 57–65, doi:10.1002/gps.3790.

28. Desveaux, L., A. Lee, R, Goldstein, and D. Brooks, “Yoga in the Management of Chronic Disease: A Systematic Review and Meta-analysis.” Medical Care 53, no. 7 (July 2015): 653–661, doi:10.1097/ MLR.0000000000000372.

29. Hartley, L., et al., “Yoga for the Primary Prevention of Cardiovascular Disease,” Cochrane Database of Systematic Reviews 5 (May 13, 2014): CD010072, doi:10.1002/14651858.CD010072.pub2.

30. Lu, Y. – H., B. Rosner, G. Chang, and L. M. Fishman, “Twelve-Minute Daily Yoga Regimen Reverses Osteoporotic Bone Loss,” Topics in Geriatric Rehabilitation 32, no. 2 (April 2016): 81–87.

31. Liu, X., et al., “A Systematic Review and Meta-analysis of the Effects of Qigong and Tai Chi for Depressive Symptoms,” Complementary Therapies in Medicine 23, no. 4 (August 2015): 516–534, doi:10.1016/j.ctim.2015.05.001.

32. Freire, M. D., and C. Alves, “Therapeutic Chinese Exercises (Qigong) in the Treatment of Type 2 Diabetes Mellitus: A Systematic Review,” Diabetes & Metabolic Syndrome: Clinical Research & Reviews 7, no. 1 (March 2013): 56–59, doi:10.1016/j.dsx.2013.02.009.

33. Ho, R. T. H., et al., “A Randomized Controlled Trial of Qigong Exercise on Fatigue Symptoms, Functioning, and Telomerase Activity in Persons with Chronic Fatigue or Chronic Fatigue Syndrome,” Annals of Behavioral Medicine 44, no. 2 (October 2012): 160–170, doi:10.1007/s12160–012–9381–6.

34. Ornish D., et al., “Effect of Comprehensive Lifestyle Changes on Telomerase Activity and Telomere Length in Men with Biopsy-Proven Low-Risk Prostate Cancer: 5-Year Follow-Up of a Descriptive Pilot Study,” Lancet Oncology 14, no. 11 (October 2013): 1112–1120, doi: 10.1016/S1470–2045 (13) 70366–8.

Тест. Как поживают ваши теломеры?

Факторы риска и защиты

1. Ahola, K., et al., “Work-Related Exhaustion and Telomere Length: A Population-Based Study,” PLOS ONE 7, no. 7 (2012): e40186, doi:10.1371/journal.pone.0040186.

2. Damjanovic, A. K., et al., “Accelerated Telomere Erosion Is Associated with a Declining Immune Function of Caregivers of Alzheimer’s Disease Patients,” Journal of Immunology, 179 no. 6 (September 15, 2007): 4249–4254.

3. Geronimus, A. T., et al., “Race-Ethnicity, Poverty, Urban Stressors, and Telomere Length in a Detroit Community-Based Sample,” Journal of Health and Social Behavior 56, no. 2 (June 2015): 199–224, doi:10.1177/0022146515582100.

4. Darrow, S. M. et al., “The Association between Psychiatric Disorders and Telomere Length: A Meta-analysis Involving 14,827 Persons,” Psychosomatic Medicine 78, no. 7 (September 2016): 776–87, doi:10.1097/ PSY.0000000000000356; and Lindqvist et al. “Psychiatric Disorders and Leukocyte Telomere Length: Underlying Mechanisms Linking Mental Illness with Cellular Aging,” Neuroscience & Biobehavioral Reviews 55 (August 2015): 333–64, doi:10.1016/j.neubiorev.2015.05.007.

5. Mitchell, P. H., et al., “A Short Social Support Measure for Patients Recovering from Myocardial Infarction: The ENRICHD Social Support Inventory,” Journal of Cardiopulmonary Rehabilitation 23, no. 6 (November – December 2003): 398–403.