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4. J. Labbadia and R. I. Morimoto, «Repression of the Heat Shock Response Is a Programmed Event at the Onset of Reproduction», Molecular Cell (July 22, 2015), pii: S1097–2765 (15) 00499–2, doi:10.1016/j.molcel.2015.06.027 (Epub ahead of print).

5. O. R. Jones et al., «Diversity of Ageing Across the Tree of Life», Nature 505, no. 7482 (January 9, 2014): 169–73, doi:10.1038/nature12789, Epub December 8, 2013. См. также «Surprising Diversity in Aging Revealed in Nature», Phys.org, December 8, 2013, http://phys.org/news/201312diversityagingrevealednature.html?.

6. D. W. Belsky et al., «Quantification of Biological Aging in Young Adults», Proceedings of the National Academy of Sciences of the United States of America 112, no. 30 (July 28, 2015): E4104–10, doi:10.1073/pnas.1506264112, Epub July 6, 2015.

7. Ariana Eunjung Cha, «Study of 1,000 38YearOlds Shows ‘Biological Age’ Ranges from 30 to 60», Washington Post, July 7, 2015, www.washingtonpost.com/news/toyourhealth/wp/2015/07/07/studyof100038yearoldsshowsbiologicalagerangesfrom30to60/?.

8. Belsky et al., «Quantification of Biological Aging in Young Adults».

9. Больше о калькуляторе «сердечного возраста» вы можете узнать по адресу www.cdc.gov/vitalsigns/cardiovasculardisease/heartage.html.

10. Больше информации об услугах Foundation Medicine вы узнаете на сайте www.foundationmedicine.com.

11. Некоторые называют иммунотерапию «пятым столпом» лечения рака после операций, химиотерапии, радиотерапии и лекарств вроде «Гливека» и «Герцептина», атакующих мутации раковых клеток.

12. L. M. Abegglen et al., «Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans», JAMA. Published online October 08, 2015. doi:10.1001/jama.2015.13134. См. также Michael Sulak et al., «TP53 Copy Number Expansion Correlates with the Evolution of Increased Body Size and an Enhanced DNA Damage Response in Elephants», Cold Springs Harbor Laboratory, bioRxiv, a prepublication posting, October 6, 2015, http://biorxiv.org/content/early/2015/10/06/028522.

13. D. P. Lane, «Cancer. p53, Guardian of the Genome», Nature 358, no. 6381 (July 2, 1992): 15–6.

14. Отличный рассказ о жизни и карьере Массаге Соле вы найдете в статье Elizabeth DevitaRaeburn, «The Unintentional Scientist: Joan Massagué Was Having Too Much Fun to Notice He Was Building a Career – and Solving Problems of Cell Signaling and Cancer Metastasis», Howard Hughes Medical Institute Bulletin, August 2008, https://web.archive.org/web/20120905041353/http://www.hhmi.org/bulletin/aug2008/pdf/Scientist.pdf, статья открыта 7 августа 2015 года.

15. J. L. Watkins et al., «Clinical Impact of Selective and Nonselective BetaBlockers on Survival in Patients with Ovarian Cancer», Cancer (August 24, 2015), doi: 10.1002/cncr.29392. Epub ahead of print.

16. B. Dulken and A. Brunet, «Stem Cell Aging and Sex: Are We Missing Something?» Cell Stem Cell 16, no. 6 (June 4, 2015): 588–90, doi:10.1016/j.stem.2015.05.006.

17. C. Zhang et al., «Genetic Determinants of Telomere Length and Risk of Common Cancers: A Mendelian Randomization Study», Human Molecular Genetics 24, no. 18 (September 15, 2015): 535666, doi: 10.1093/hmg/ddv252. Epub 2015 Jul 2.

18. «Antimicrobial Resistance: Tackling a Crisis for the Health and Wealth of Nations», Review on Antimicrobial Resistance, chaired by Jim O’Neill, December 2014, http://amrreview.org/sites/default/files/AMR%20Review%20Paper%20%20Tackling%20a%20crisis%20for%20the%20health%20and%20wealth%20of%20nations_1.pdf, статья открыта 7 августа 2015 года.

19. Kirandeep Bhullar et al., «Antibiotic Resistance Is Prevalent in an Isolated Cave Microbiome», PLOS ONE 7, no. 4 (2012): E34953, doi:10.1371/journal.pone.0034953.

20. L. L. Ling et al., «A New Antibiotic Kills Pathogens Without Detectable Resistance», Nature 517, no. 7535 (January 22, 2015): 455–59, doi:10.1038/nature14098, Epub January 7, 2015.

Глава 3. Будущий вы

1. G. J. Xu et al., «Viral Immunology. Comprehensive Serological Profiling of Human Populations Using a Synthetic Human Virome», Science 348, no. 6239 (June 5, 2015): aaa0698, doi:10.1126/science.aaa0698. См. также Denise Grady, «New Test Traces a Person’s Virus History», Boston Globe, June 5, 2015, www.bostonglobe.com/business/2015/06/04/singletestforallvirusexposureopensdoorsforresearchers/uZ7DwhaIHXha1ux1dtdb4K/story.html?.

2. J. Suez et al., «Artificial Sweeteners Induce Glucose Intolerance by Altering the Gut Microbiota», Nature 514, no. 7521 (October 9, 2014): 181–86, doi:10.1038/nature13793, Epub September 17, 2014.

3. N. H. Shah et al., «Proton Pump Inhibitor Usage and the Risk of Myocardial Infarction in the General Population», PLOS ONE 10, no. 6 (June 10, 2015): E0124653, doi:10.1371/journal.pone.0124653, eCollection 2015. См. также Kristin Magaldi, «Common OTC Antacids Increase Risk of Heart Attack up to 21 %», Medical Daily, June 10, 2015, www.medicaldaily.com/commonotcantacidsincreaseriskheartattack21337594?.

4. Y. T. Ghebremariam et al., «Unexpected Effect of Proton Pump Inhibitors: Elevation of the Cardiovascular Risk Factor Asymmetric Dimethylarginine», Circulation 128, no. 8 (August 20, 2013): 845–53, doi:10.1161/CIRCULATIONAHA.113.003602, Epub July 3, 2013.

5. Dominic Basulto, «How IBM Watson Will Impact Our Fight Against Cancer», Washington Post, May 6, 2015.

6. «Behind the Bloodshed: The Untold Story of America’s Mass Killings», USA Today, www.gannettcdn.com/GDContent/masskillings/index.html# frequency, статья открыта 7 августа 2015 года. См. также www.usatoday.com/story/news/nation/2013/09/16/masskillingsdatamap/2820423, статья открыта 7 августа 2015 года.

7. C. Dufouil et al., «Older Age at Retirement Is Associated with Decreased Risk of Dementia», European Journal of Epidemiology 29, no. 5 (May 2014): 353–61, doi:10.1007/s1065401499063, Epub May 4, 2014.

8. A. L. Hansell et al., «Aircraft Noise and Cardiovascular Disease Near Heathrow Airport in London: Small Area Study», British Medical Journal 34 (October 8, 2013): F5432, doi:10.1136/bmj.f5432.

9. A. W. Correia et al., «Residential Exposure to Aircraft Noise and Hospital Admissions for Cardiovascular Diseases: MultiAirport Retrospective Study», British Medical Journal 347 (October 8, 2013): F5561, doi:10.1136/bmj.f5561.

10. Gina Kolata, «Antibiotics Are Effective in Appendicitis, Study Says», New York Times, June 17, 2015, A17. См. также P. Salminen et al., «Antibiotic Therapy Vs. Appendectomy for Treatment of Uncomplicated Acute Appendicitis: The APPAC Randomized Clinical Trial», Journal of the American Medical Association 313, no. 23 (June 16, 2015): 2340–48, doi:10.1001/jama.2015.6154.